Research shows people with high omega-3 index less likely to die from COVID-19

Omega 3 - come and get it
Omega 3 – come and get it


Researchers with the Fatty Acid Research Institute (FARI) and collaborators at Cedars-Sinai Medical Center in Los Angeles and in Orange County, CA, have published the first direct evidence that higher omega-3 blood levels may reduce risk for death from COVID-19 infection. The report was published in the journal Prostaglandins, Leukotrienes and Essential Fatty Acids on January 20, 2021.

There are several papers in the medical literature hypothesizing that omega-3 fatty acids should have beneficial effects in patients with COVID-19 infection, but up until now, there have been no published peer-reviewed studies supporting that hypothesis.

This study included 100 patients admitted to the hospital with COVID-19 for whom admission blood samples had been stored. Clinical outcomes for these patients were obtained and blood was analyzed for the Omega-3 Index (O3I, red blood cell membrane EPA+DHA levels) at OmegaQuant Analytics (Sioux Falls, SD). Fourteen of the patients died.

The 100 patients were grouped into four quartiles according to their O3I, with 25% of the patients in each quartile. There was one death in the top quartile (i.e., 1 death out of 25 patients with O3I>5.7%), with 13 deaths in the remaining patients (i.e., 13 deaths out of 75 patients with O3I<5.7%).

In age-and-sex adjusted regression analyses, those in the highest quartile (O3I >5.7%) were 75% less likely to die compared with those in the lower three quartiles (p=0.07). Stated another way, the relative risk for death was about four times higher in those with a lower O3I (<5.7%) compared to those with higher levels.

“While not meeting standard statistical significance thresholds, this pilot study – along with multiple lines of evidence regarding the anti-inflammatory effects of EPA and DHA – strongly suggests that these nutritionally available marine fatty acids may help reduce risk for adverse outcomes in COVID-19 patients. Larger studies are clearly needed to confirm these preliminary findings,” said Arash Asher, MD, the lead author on this study.

Agreeing with Dr. Asher, cardiology researcher and co-developer with Dr. Harris of the Omega-3 Index, Clemens von Schacky, MD, (CEO, Omegametrix GmbH, Martinsried, Germany, and not involved with the study) said, “Asher et al have demonstrated that a low Omega-3 Index might be a powerful predictor for death from COVID-19. Although encouraging, their findings clearly need to be replicated.”

Omega-3 expert James H. O’Keefe, Jr., MD, (Director of Preventive Cardiology, Saint Luke’s Mid America Heart Institute, Kansas City, MO, and also not involved with the study) observed, “An excessive inflammatory response, referred to as a ‘cytokine storm,’ is a fundamental mediator of severe COVID-19 illness. Omega-3 fatty acids (DHA and EPA) have potent anti-inflammatory activities, and this pilot study provides suggestive evidence that these fatty acids may dampen COVID-19’s cytokine storm.”

The FARI research team is currently seeking funding to expand upon these preliminary observations. Individuals and organizations that want to support this research are encouraged to visit FARI’s donations page.

Multiple Sclerosis Supplements (Vitamin D, Omega-3, Biotin, Vitamin A, Co Q10, and more)

Multiple Sclerosis Supplements (Vitamin D, Omega-3, Biotin, Vitamin A, Co  Q10, and more) - YouTube

Timestamps:

1:05 Vitamin D

3:48 Omega-3

7:22 Biotin

9:28 Vitamin A

10:23 Neuropathic pain

11:41 Fatigue

12:28 Muscle Spasms/Spasticity

13:05 Migraine

This video summarizes the best-available evidence regarding supplement for MS and MS symptoms.

Over 50s feel fitter and healthier than the 30-somethings – Find out how you can to here!

According to new research, Brits aged over 50 feel they are in better shape than the nation’s 30-somethings.

65% also revealed they view 40 as the average prime of life, with two-thirds of

Omega 3 - come and get it

Omega 3 – come and get it

British 50-somethings stating they feel up to 10 years younger than they are actually are.

Yet in contrast, the average 35-39 year old feels just one year better off than their real age.

A combination of active pursuits like gardening, healthy diets and regular fish oil or algae-based Omega-3 DHA and EPA supplements means that nearly 2-in-5 (37%) of 50-59 year olds say they feel fit and well, compared to 1-in-3 (33%) of those aged 35-39.

A new survey spoke to more than 1,000 UK residents aged 35 or over and found that as a nation, we are staying active much later into life. Specifically, results found that individuals who take Omega-3 supplements feel on average three years younger than those who don’t.

We spoke to Lucy Jones a nutritionist at Nutrifit Health and Dr. Ali Kavandi who is Cardiologist at Royal United Hospital Bath NHS Foundation Trust.

PATIENTTALK.ORG: So we are talking about some research that suggests over 50’s feel fitter and healthier then over 30 somethings and I was hoping Dr Kavandi you could just run us through the report that’s called “The Prime of Life Report”?

KAVANDI:  Yes no problem.  So, I mean, this was very interesting, it was a survey essentially and I think the thing I’ve picked up on and what I think is the most interesting thing is the perception of the public and our patients about health and links between diet and health in the long term.  What becomes very clear in terms of the headline findings is that there is a lot of confusion about health and a diet that is linked to health.  Most people’s definition of health in fact is confused and it seems that in the modern world most people think of health in terms of what you would think of wellbeing so they think a heathy diet is one that leads to subjective things like more energy, better hair, clean skin.  Whereas from a medical perspective we are very clear the definition of health is the prevention of illness so what we regard to be a healthy diet is one that prevents illness down the line and from my perspective especially cardiovascular illness.


PATIENTTALK.ORG: That is very interesting. Lucy I was wondering if you could perhaps expand on that a bit this idea between what sorts of makes you feel perky and what is actually fundamentally good for you and nutrition?

JONES:  Well this is exactly is 68% of people that are saying they feel heathier and are fitter were actually looking at more appearance focused health concerns so things like their teeth, their skin, their hair whilst only 7% were concerned about their heart health and we see this a lot that actually the foundations of our health, the things we really need to protect our heart, our liver, our brains we often don’t think about problems have already happened and when it comes to nutrition and lifestyle prevention is so much better than cure and unfortunately for many of us we start turning our attention to it too late. We know that damage starts to build up in very early, as early as your twenties and the steps you take then to have a positive change on your diet, to start regular exercise, will really lay the foundations of better health when you get into your 50’s and 60’ and we really need  a culture change to support that.  That people need to be paying attention to their long term health. It might not make a change to how you feel tomorrow, even though this survey suggested it does. People who were taking Omega 3 supplements this survey for feeling 3 years younger than people who didn’t and this might be a reflection that if you start taking positive steps for your health you in fact feel better for it.

PATIENTTALK.ORG: And Doctor Kavandi is there, why do you think over 50’s start to feel fitter and healthier then 30 something’s is it because as they get older they start to take their diet more seriously and start to take more professional advice because they just feel that’s the time you should do it and 30 something’s just feel like they have to just get on with living? Or, your experience, this research here is that people over 35 cite professionals and NHS guidelines as the most trusted source of information. Do you think people sort of start to take attention to advice a little more what’s the reason?

KAVANDI:  I mean that was a really encouraging statistic from my perspective and I think it’s true as in your younger adult years your priorities may be kind off different. You may perhaps feel invincible and your attitudes are focused towards your career or children or other things like that. As one gets older I think your health and vulnerability becomes much more real and perhaps this is emphasised by the way we work in healthcare. Once you go over the age of 40 we start to do health checks for example and we actually diagnose cardiovascular risk factors things like high blood pressure, high cholesterol, we tell patients about these things and at that point they really have emotional guides to make positive changes.  The reality is actually that 80% of all premature cardiovascular disease can be prevented through the appropriate diet.  Most cardiovascular risk factors are linked to diet and lifestyle so it’s necessarily inevitable that you will end up on tablet treatments but if you do the right things early on then you can actually reverse the process.  The problem is there is so much misinformation ibn the public space and even patients we see that are motivated to make positive changes, who want to be healthy, unfortunately sometimes do the wrong things and I think part of our emphasis is to try and highlight how important these things are, how profoundly important they can be too your long-term health but specifically revealing the thing that you can do that make a contemporary evidence based change to your health.

PATIENTTALK.ORG: Yes I remember seeing, I bumped into someone who said they were on a diet and they were eating gummy bears and I said perhaps it wasn’t the best diet to take and they said “Well it’s low in fat” so I wonder what sort of, Lucy if can you tell us why is it so hard for us to understand what is good to eat? What is a healthy diet and why there are so many strong myths about people just sort of fear fat? People don’t really take sugar seriously. People aren’t having proper portions of food.

JONES:  Well in fact this survey really back that up. 41% of people who responded to this survey couldn’t identify a single food associated with their heart health and people are really struggling to understand what should be eating.  The thing that we really have an issue with in this country is that we tend to like to have saviours and evil monsters so we have good foods and bad foods, and in fact there is no such thing. It’s not that fat is good or fat is bad. It’s the balance of nutrients in our diet and actually this is what people really struggle to understand.  We’ve got to stop demonising sugar, we’ve got to stop demonising fat and we’ve got to start thinking of people’s diets as a whole and if we think about heart health.  The most protective diet that somebody can start to adopt is a Mediterranean style so that is a diet that is based on plenty of fresh fruits and vegetables so that is dark, green leafy vegetables, dark coloured red and purple berries, nuts and seeds, beans and pulses, wholegrain so not a low carbohydrate diet but wholegrain carbohydrates.  Porridge oats we know are heart protective, they help to reduce cholesterol and people need to be more realistic about are they eating enough oily fish because the Omega 3 fatty acids present in oily fish we know protect our heart and in this country too many people are not eating enough and there is just no excuse.  If you are not eating enough oily fish because you don’t like it then there are so many other options. You can get fortified fish fingers, fortified eggs, you can even get algae based vegan supplements there is no excuse now not to be include these nutrients in your diet and people need to be aware of the profound effect it can have.

PATIENTTALK.ORG: Dr Kavandi, I was hoping you could expand on something for me.  There is this sort of idea that feeling younger doesn’t  necessary have a medical base to it so what is with the relationship with having shiner hair or something you mentioned and what’s the difference from just feeling quirky and physically feeling and being 10 years younger?

KAVANDI:  I want to emphasise that actually feeling good about your health is actually a positive thing. People who actually make proactive choices towards their health wherever they are actually evidence based or not, and feel about that are likely to continue to make positive choices. So I don’t think that per se is a bad thing but I think people if they want to be effective by their health interventions want to actually concentrate their efforts on the things that are going to make the biggest change.  For example in the cardiology community in fact the cardiovascular community over the last couple of years we have moved towards calculating a patient’s heart age and you can do this yourself, you can go online and google and heart age and work out your own heart age, and that looks at scientific cardiovascular risk factors and translates that to you know quite an attractive way of quantifying your own general health.  I think what would be interesting is to combine that heart age with people who feel well and I think some people would be surprised about their heart age. The reality is if you use that same motivation to make changes towards proper healthy foods not a gummy bear diet for example you can make massive changes to your heart age, actually see it improving in a relatively small time.  The reality is small changes in the short term can make a big difference. I will give you an example.  Lots of my patients that have problematic blood pressure for example are taking multiple tablets are life transforming for them and make a huge issue but sometimes when you address issues such as diet and weight you find that their burden of tablet treatment  reduces very, very quickly and is about a directed diet. A diet that’s based on contemporary evidence.  The other thing that I want to emphasis and actually again it parallels the gummy bear diet is that most people regard a healthy diet as a restrictive diet one where you are cutting things out.  It’s very clear that a healthy diet, a protective diet is one where you are focusing on putting good things in and often putting the good things in often displaces the bad things as well.

PATIENTTALK.ORG: Great. So if anyone wants to take a little look at this “Prime of Life” report, get a little more information to be proactive, what’s the best place to go?

KAVANDI:  Well we are actually just checking but we don’t thing “The Prime of Life” survey is actually published anywhere at the moment.

PATIENTTALK.ORG: That’s fine.

JONES:  It is available on request. What I would like to do is direct people to where they can find out more information about their heart health which is the British Heart Foundation.  They can get diet specific advice and Omega 3 specific advice from the British Dietetic Association. That’s at bda.uk.com and if they want to find out about vegan alternatives to Omega 3 fatty acids they can do so at lifesdha.com.

PATIENTTALK.ORG: That’s perfect. Thank you very much.

JONES:  Thank you.

KAVANDI:  Thank you.

Chia Seeds – Find out more about this amazing Superfood


Chia seeds

Chia seeds

As many of you will know I’m rather partial to what are called superfoods.  While, it seems, there is no formal definition of Superfood the terms is, typically, used to describe foodstuffs which have a high nutrient value.  Therefore offering greater health benefits than the run of the mill stuff we often eat.

In fact superfoods are still a bone of contention in our house.  My wife claims I secretly grated broccoli, which she hates, on her food while she was pregnant with our first child.

For more background on superfoods please have a look at https://patienttalk.org/?p=276 .  It includes links to pro and anti superfoods discussions.

But to return to the point of the blog.  Last week my wife returned home brandishing a copy of a magazine which gave a recipe for a dish which included something called chia seeds.  Which, according to the article, were superfoods?  “What on earth are Chia seeds?” I exclaimed.   To which I received the traditional “search me” look.

So I decided it was my duty, as a healthcare blogger, to find out more about the health benefits of chia seeds.  Indeed in America the chia craze has been going for a few years but it seems that Europe is about to catch up.

Chia is a member of the mint family which grows in Latin America.   Apparently   it was  a staple of Aztec and Mayan cooking. However it is the seeds themselves which are of particular interest.  Chia seeds contain:-

a)      More Omega 3 fatty acids than salmon.

b)      A great source of antioxidants.  You can read up on antioxidants here https://patienttalk.org/?p=252

c)       Very high in dietary fibre

d)      A source of calcium and iron and a number of B vitamins

e)      May lower cholesterol and help prevent heart disease

Chai seeds are often used by athletes and a table spoon of the seeds has been described as the equivalent of a smoothie of salmon and spinach.

So how do you take it?  Well it is a common addition to smoothies and health drinks.  Have a look at https://patienttalk.org/?p=638 for more info.

The downside of chai seeds is the cost.  But if they take off we can only hope it will come down.

In fact today is going to be the first time I’ve tried chai seeds.  I’ll be using this recipe for BLACK BEAN SOUP WITH SUPER CHIA GARNISH for Stylist Magazine which can be found here http://www.stylist.co.uk/life/recipes/black-bean-soup-with-super-chia-garnish.  Once we have tried it I’ll give you an update.  Given that I love black beans I’m sure I’ll be a fan.

If you have used chia seeds it would be great if you can tell us how you found them using the comments box.  If you have any recipes then please share them as well

Many thanks in advance.


Pain! Some natural treatments for pain.




pain-management1There are many who are dissatisfied with conventional treatments for pain and are looking for more natural ways to find relief.  Many use dietary supplements as part of the pain management strategies.




As part of our on-going series of blogs on pain management we would like to introduce to you a few natural remedies for pain.  In a previous blog we explored food which helped pain (see https://patienttalk.org/?p=507). In this blog we are looking at naturally occurring substances which can be used to provide relief from pain.   In this case they may be available either as food or as a dietary supplement.  For most the key issue is that the treatments and products they use are not synthesised chemicals:-

a)      Capsaicin.  Comes from chilli peppers and can be used on the skin to treat pain. Including rheumatoid arthritis and diabetic neuropathy.

b)      Vitamin D.   We covered Vitamin D in an earlier blog this year (https://patienttalk.org/?p=300).  It is available free from the sun as well in “paid for” supplements.

c)       Omega-3s or fish oil. This old favourite seems always to come up when health is discussed.  While an effective anti-inflammatory it now seems to help people with neuropathic and fibromyalgia pains.  It can be taken in concentrated form as a supplement but I still prefer a smoked salmon bagel.

d)      Glucosamine sulphate. This dietary supplement is often recommended for people with osteoarthritis.

e)      Methylsulfonyl-methane.  Also for osteoarthritis it helps reduce joint pain.

Please note that these products are dietary supplements rather than medications. Before using them at all we would recommend you speak with a qualified healthcare professional.




Of course these are only five among many.  This is where you come in. It would be great if you could share your experiences of using dietary supplements to help manage pain. You might like to consider some of the following questions:-

1)      What is the main medical condition which causes you pain?

2)      How do you manage your pain?  What role do dietary supplements play in your pain management?

3)      How successful have they been?

4)      Are there any dietary supplements you would recommend?

Feel free to use the comments box below to share your story and to add any links you think may be of interest.

Many thanks in advance.