Weight training improves symptoms of anxiety and depression in old people, study confirms

Brazilian researchers analyzed more than 200 articles on the subject and identified the types of training most indicated for these cases.

Weight training can help reduce body fat and increase muscle strength and mass in older people, contributing to functional autonomy and avoiding falls and injury. Furthermore, recent studies have shown that it can also benefit the mental health of older people, especially those who suffer from anxiety and depression.

These benefits were confirmed by a study reported in the journal Psychiatry Research. The study involved a systematic review and meta-analysis of more than 200 articles. The analysis was conducted by Paolo Cunha, a postdoctoral fellow with a scholarship from FAPESP at the Albert Einstein Jewish-Brazilian Institute of Education and Research (IIEPAE) in São Paulo, Brazil. 

“Resistance training has been shown to be one of the most effective non-pharmacological strategies for healthy aging. It promotes countless health benefits, including improvements to mental health,” Cunha said.

The findings of the study are highly promising, he continued. Besides improvements to symptoms of anxiety and depression in the general population, weight training appears to have a more significant effect on people with a confirmed diagnosis of anxiety or depression disorder.

“Epidemiological studies have shown that the decrease in muscle strength and mass that occurs naturally as we age may be associated with an increase in mental health problems, given the existence of various physiological mechanisms that bring about functional and structural changes and that are controlled by the brain,” Cunha said.

Another important mental health benefit, he added, is that when weight training is done in a group, it contributes to more social interaction among those involved.

Recommended exercises

The investigation also pointed to the best ways of structuring one’s training to improve mental health. “How the training is done appears to influence the results achieved. The information obtained so far suggests that older people should ideally do weight training exercises three times a week, with three sets of each exercise and sessions that are not too long – six exercises would seem to be sufficient. Do less, but do it well: a short set produces better results. This is meaningful information, as we lack guidelines with specific recommendations for resistance training that focuses on mental health parameters,” Cunha said.

While there are many possible ways to prescribe resistance training programs designed to improve the health, autonomy and quality of life for older people, most result directly or indirectly in improvements to symptoms of anxiety and depression, regardless of the intensity and volume of the exercises involved, according to Edilson Cyrino, last author of the article and principal investigator for the study. He is a professor at the State University of Londrina (UEL) and coordinates the Active Aging Longitudinal Study, a project begun in 2012 to analyze the impact of resistance training on parameters relating to the health of older women.

Another point observed by the researchers was that the use of training machines and free weights appears to be more beneficial for mental health than exercises that involve elastic bands or calisthenics (using the weight of the person’s body), for example. 

“We don’t have statistics comparing the two kinds of training, but the analysis showed that resistance training with weights and other gear is more effective in terms of improving the mental health of older people, largely because the intensity and volume of the exercises can be more precisely controlled,” Cunha explained.

Find out about the benefits of resistance exercise training in treatment of anxiety and depression.

A new study by researchers at University of Limerick in Ireland and at Iowa State University has demonstrated the impact resistance exercise training can have in the treatment of anxiety and depressive symptoms.
A new study by researchers at the University of Limerick in Ireland and at Iowa State University has demonstrated the impact resistance exercise training can have in the treatment of anxiety and depressive symptoms.

A new study by researchers at the University of Limerick in Ireland and at Iowa State University has demonstrated the impact resistance exercise training can have in the treatment of anxiety and depressive symptoms.

The new study provides evidence to support the benefits resistance exercise training can have on anxiety and depression and offers an examination of possible underlying mechanisms.

The research, published in the Trends in Molecular Medicine journal, was carried out by Professor Matthew P Herring at the University of Limerick and Professor Jacob D Meyer at Iowa State University.

The researchers said there was “exciting evidence” that resistance exercise training may be an accessible alternative therapy to improve anxiety and depression-like more established therapies while also improving other important aspects of health.

Dr Herring explained: “Anxiety and depressive symptoms and disorders are prevalent and debilitating public health burdens for which successful treatment is limited.

“The healthful benefits of resistance exercise training, or muscle-strengthening exercise involving exerting force against a load repeatedly to generate a training response, are well-established,” said Dr Herring, Associate Professor in the Physical Activity for Health Research Centre, Health Research Institute, and Department of Physical Education and Sport Sciences within the Faculty of Education and Health Sciences in UL.

“However, the potential impact of resistance exercise training in the treatment of anxiety and depressive symptoms and disorders remains relatively understudied. Moreover, the plausible psychobiological mechanisms that help us better understand how and why resistance exercise training may improve these mental health outcomes are poorly understood.”

The researchers argue that, while the available studies in this area are focused on relatively small sample sizes, there is sufficient evidence from previous and ongoing research at UL and the National Institute of Health-funded research with Dr Meyer and colleagues at Iowa State University to suggest that resistance exercise training does improve anxiety and depressive symptoms and disorders – though disorders themselves are scarcely studied.

“There is a critical need for confirmatory, definitive trials that adequately address limitations, including small sample sizes, but the limited evidence available to us provides initial support for the beneficial effects of resistance exercise training on these mental health outcomes, including increased insulin-like growth factor 1, cerebrovascular adaptations, and potential neural adaptations influenced by controlled breathing inherent to resistance exercise,” Dr Herring explained.

“We are tremendously excited to have what we expect to be a highly cited snapshot of the promising available literature that supports resistance exercise training in improving anxiety and depression. 

“Notwithstanding the limitations of the limited number of studies to date, there is exciting evidence, particularly from our previous and ongoing research of the available studies, that suggests that resistance exercise training may be an accessible alternative therapy to improve anxiety and depression.

“A more exciting aspect is that there is substantial promise in investigating the unknown mechanisms that may underlie these benefits to move us closer to maximizing benefits and to optimising the prescription of resistance exercise via precision medicine approaches,” Dr Herring added.

Professor Meyer, a co-author on the study, said: “The current research provides a foundation for testing if resistance training can be a key behavioural treatment approach for depression and anxiety.

“As resistance training likely works through both shared and distinct mechanisms to achieve its positive mood effects compared to aerobic exercise, it has the potential to be used in conjunction with aerobic exercise or as a standalone therapy for these debilitating conditions.

“Our research will use the platform established by current research as a springboard to comprehensively evaluate these potential benefits of resistance exercise in clinical populations while also identifying who would be the most likely to benefit from resistance exercise.”

MU study shows blood pressure drug can reduce anxiety for autistic folks

Findings reveal propranolol may help kids and young adults with autism who struggle with anxiety.
Findings reveal propranolol may help kids and young adults with autism who struggle with anxiety.

A new study at the University of Missouri’s Thompson Center for Autism and Neurodevelopment found that propranolol, a medication that treats high blood pressure, can also help lower anxiety for autistic kids and young adults).

Given that some autistics tend to struggle with anxiety at a far greater rate than their neurotypical peers, the new finding can significantly help such individuals in the autistic community. David Beversdorf, a clinician at the Thompson Center, led the study, which involved 69 patients over a three-year span. Compared to a placebo group, the participants who received propranolol showed significantly reduced anxiety levels at their 12-week check-up appointments while receiving the medication. The study also examined if there were significant changes in the individuals’ social communication skills, but no significant changes were found.

“The findings show that propranolol could serve as a helpful intervention for reducing anxiety for individuals with autism,” said Beversdorf, who also has appointments in the MU School of Medicine and the MU College of Arts and Science. “This drug has been around since the 1960s and is very inexpensive. Up until now, we haven’t had any known drugs that target psychiatric issues specifically for individuals with autism, so these results are very promising and can support future research.”

As a clinician, Beversdorf has seen firsthand the positive benefits propranolol can have in improving the overall quality of life for some autistic folks and their families.

“As researchers, we try our best to improve the lives of our patients, and it feels rewarding to help out,” said Beversdorf, who is a professor of radiology, neurology and psychological sciences as well as the William and Nancy Thompson Endowed Chair in Radiology. “I went into the field of neurology knowing I wanted to try to find new treatment options and interventions to benefit autitic folks.”

Study explores how changing autism traits are linked to mental health conditions.

Findings suggest that some restrictive and repetitive behaviors may help reduce anxiety for autistic individuals
Findings suggest that some restrictive and repetitive behaviors may help reduce anxiety for autistic individuals

A long-term study by UC Davis Health researchers sheds new light on the relationship between autism traits and mental health in middle childhood. The paper, published in the journal Autism, finds that changes in core autism characteristics are related to whether children develop additional mental health challenges during their elementary school years.

“Our findings suggest that different aspects of a child’s development may affect each other over time,” explained Einat Waizbard-Bartov, a doctoral researcher in developmental psychology at the UC Davis MIND Institute and the lead author on the paper. “Core autism traits and mental health challenges likely interact throughout development.”

A key finding was that a reduction in restrictive and repetitive behaviors during elementary school was linked to the emergence of mental health challenges, lending support to the idea that these behaviors may benefit autistic individuals. An increase in social-communication difficulties during this time was also linked to anxiety and other mental health challenges.

Study design

Waizbard-Bartov has published previous research showing autism characteristics can change significantly from ages 3 to 11.

The current study included 75 autistic children ages 6 to 11, including 15 girls. All were part of the MIND Institute’s Autism Phenome Project, a large, long-term study aimed at identifying different subtypes of autism.

Through parental interviews and questionnaires, the research team evaluated the children for mental health symptoms and restricted and repetitive behaviors, which can include seeking sensory stimulation, hand-flapping or sticking to set routines.  

They tracked changes in autism characteristics using the Autism Diagnostic Observation Schedule Calibrated Severity Score.

About a fifth (21%) of the youth had more severe social-communication difficulties, as well as an increase in anxiety, ADHD and behavioral challenges. In contrast, nearly 23% had decreased restricted and repetitive behaviors but higher anxiety levels by age 11. Nearly all — 94% —met the criteria for an anxiety disorder.

About a third of the participants had both decreasing restricted and repetitive behaviors and increased social-communication difficulties.

“We were pleased to see that our results confirmed what has been suspected by other autism researchers and clinicians as well as autistic individuals, that some forms of restricted and repetitive behaviors can potentially help to self-soothe,” said David Amaral, distinguished professor in the Department of Psychiatry and Behavioral Sciences, MIND Institute faculty member and senior author on the paper.

Waizbard-Bartov notes that the findings question the wisdom of therapies that try to eliminate these behaviors.

“In light of this, when thinking about interventions, it might be that trying to eliminate repetitive behaviors without providing alternative self-soothing tools is not the ideal way to go,” she said.

The study is the first, to the authors’ knowledge, to demonstrate an association between mental health challenges and increases in the severity of social-communication difficulties for autistic children. 

“This occurred in children who showed decreases in core autism traits during early childhood and whose cognitive functioning was in the typical range. We don’t currently understand why this happened. One possibility is that due to their relatively high cognitive ability, they became aware of their social challenges, and this may have contributed to increasing anxiety,” Amaral explained. “It’s definitely an area where we need more research.”