Novel Gene Therapy Reverses Paralysis in Mice with Multiple Sclerosis

Multiple sclerosis and gene therapy

Multiple sclerosis and gene therapy

Just read this fascinating article in The Specialty Pharma Times.

“Scientists employed a novel gene therapy technique to reverse and prevent the development of multiple sclerosis (MS) in mice.
For the study, published in Molecular Therapy, investigators used the adeno-associated virus to deliver a gene responsible for a brain protein to the livers of the mouse models. The gene was targeted to the liver because it can induce immune tolerance, and the adeno-associated virus jumpstarted the production of regulatory T cells.

“Using a clinically tested gene therapy platform, we are able to induce very specific regulatory cells that target the self-reactive cells that are responsible for causing multiple sclerosis,” said investigator Brad E. Hoffman, PhD.

Read the rest here.”