Some Mutations Tied to Autism May Be Passed Down from Fathers The findings go against previous studies that suggest mutations are inherited from mothers

Autism and genetics

Autism and genetics

 

Some children with autism carry rare mutations in DNA segments that flank genes and control their expression—and they tend to inherit these mutations from their unaffected fathers, according to a study published today in Science1.

The finding is unexpected because most studies implicate mutations inherited from mothers in autism risk. For this reason, some experts are skeptical of the results.

The study is the largest yet to explore how mutations outside of genes contribute to autism: It is based on an analysis of 9,274 whole genomes. And it focuses on ‘structural variants’—deletions or duplications in DNA—in these noncoding regions. Once dismissed as ‘junk DNA,’ some of these regions are now known to control the expression of genes.

“These are the types of variants which, before, if you did clinical genetic testing, you would ignore,” says lead investigator Jonathan Sebat, chief of the Beyster Center for Genomics and Neuropyschiatric Diseases at the University of California, San Diego.

The variants overall account for only a small proportion of individuals with autism, however: an estimated 0.39 to 1.13 percent.

Read the full article here.

Jason Infinger Creates First-Ever Autism Census and Autism Lab for Parents With Children on the Autism Spectrum

Jason Infinger

Jason Infinger

 

On Nov. 7, 2012, Jason Infinger and his wife Patricia received a letter in the mail — their son had autism.

As they sought help post-diagnosis, they were shocked at how little support there was specifically for the parents of children with autism. They were overwhelmed, confused and frustrated. There was too much red tape and too few answers to their practical questions and needs.

“Nobody was talking about the emotional journey we experience after the diagnosis,” said Jason. “Except the other parents.”

I had a vision of bringing parents together in one place, where they can learn strategies from each other, be part of a supportive community, navigate the emotional journey with others who have the same journey, and save time and money,

JASON INFINGER

FOUNDER, AUTISM CENSUS AND THE AUTISM LAB

An entrepreneur at heart, Jason started his first business at 14 years old. But his greatest accomplishment yet is as a husband and father of two amazing boys. Ever the creative problem solver, Jason took action once again — planning, collaborating and executing plans to create the kind of autism support he knew he, his wife and the world needed.

“Finding the best care and treatment for your beloved child is time-consuming, expensive and ridiculously confusing,” he said. “Time is an important concern for working families and the cost is overwhelming and creates family hardships.”

Jason knew the support system he would create had to be parent-focused and simple to use. His strategy was to provide empowering resources to parents with autistic children to help them be at their best. It had to simplify the parents’ lives by helping them navigate an autism diagnosis.

“I had a vision of bringing parents together in one place, where they can learn strategies from each other, be part of a supportive community, navigate the emotional journey with others who have the same journey, and save time and money,” he said. “Parents have to be able to help themselves before they can help their child.”

Jason created the first-ever Autism Census (autismcensus.com) to compile a platform to capture critical data, where parents with children on the autism spectrum can fill out the census, share their stories and find the resources targeted to their needs. He knows that by doing this, they will help other families experience a breakthrough, inspire others to keep going and help change someone’s life.

Once parents share their stories on the Autism Census, they receive a free e-book – “The Best Advice I Got About Autism: Wisdom from Extraordinary Parents and Professionals.” It’s a collection of powerful testimonies and expert advice, which is sorely lacking at this time. Any parent can submit a story or piece of advice that has helped them along the journey.

Jason also created The Autism Lab (theautismlab.com) as a place where parents can stay current on research, therapies and treatments, and that can help them uncover options that are best for their child through things like the “Ask About Autism” show and frequent blogs and videos. He plans to offer ongoing support and access through The Autism Lab PRIME membership, online courses and events.

He is currently working toward the launch of the first-ever Autism Answers Report, created from all of the information pulled to-date from the Autism Census.

Social Jetlag: No Travel Required – Is this true for people on the autism spectrum?

When you think of jetlag, you probably imagine the effects of a flight and travel on the body. However, there is another type of jetlag – social jetlag, which can have even more worrisome effects than its jet setting counterpart. Biz Brain has created an infographic entitled “Social Jetlag: No Travel Required”, explaining what social jetlag is, how to recognize it, and how to avoid it.

Probably you cannot wait for the weekend so you can stay up late and sleep in the next morning. Check out the infographic below and learn about social jetlag, how it affects businesses and how wise employees and entrepreneurs can try to avoid it.

If you don’t know the definition of social jetlag this the right infographic for you.

Social Jetlag: No Travel Required

“A Look Inside an Autism-Friendly Workplace and Culture”


#

Autism and work

Autism and work

Last week, I was in New York and had the opportunity morning to tour a true “autism-friendly workplace”—one that differs not only from most workplaces today but also from most workplaces that describe themselves as autism-friendly. I think you’ll be interested, whether you have a connection to autism or not.

A little background. The previous afternoon, I had joined 12 autism employment practitioners from throughout the New York area at the Duane Morris LLP offices on Broadway near 46th. In attendance were representatives of Integrate, Job Path, Goodwill NY, Spectrum Designs, Best Buddies, and Extraordinary Ventures NY. David Kearon of Autism Speaks, the person most at the center of autism initiatives nationwide, brought us together.

Our discussion started with the enormous grassroots activity of the past few years, the expanding corporate autism employment initiatives, and the explosion of autism in popular culture. Our focus, though, became workplace culture. Many in our autism community did get jobs, only to lose them shortly thereafter. So much of current workplace culture makes retention of adults on the autism spectrum an uphill struggle.
Read the full article here

Creating Normalcy With ‘Sesame Street’ – Introducing Character With Autism

Sesame Street Meet Julia

Sesame Street Meet Julia

In 2017, PBS revealed their newest character for the famed show Sesame Street, and she happened to be a 4-year old girl named Julia.

What was unique about Julia? She has Autism.

Using some of the typical indicators of a child with Autism, the show illustrates some of the things that may happen when interacting with a child that has Autism. For example, Julia does not react to things the same way around her. But that doesn’t stop the rest of the friends on Sesame Street from trying to befriend her.

She became a staple in the current cast that runs today and breaks the stigma of having children learn about different disabilities and learning curves that people are born with. The character creates that normalcy within the classroom and makes children more familiar with Autism in this way.

Read the full article here