Self-guided, online, therapy-based interventions may be effective in improving symptoms of fatigue in patients with multiple sclerosis (MS), according to the results of a study reported in the Journal of Neurology, Neurosurgery, and Psychiatry.

Fatigue is significantly disabling in patients with MS. Therapy may be used in management; however, patients are often limited from participation in one-on-one, office-based appointments due to their symptoms, costs, and the availability of qualified professionals.

Investigators designed a parallel-group, 2-arm, randomized controlled trial to evaluate ELEVIDA, an online fatigue management program based on cognitive behavioral therapy and other therapy-based strategies.

Patients were recruited online through the German MS society website and randomly assigned (1:1) to one of two groups: ELEVIDA (n=139, 82% female, median patient determined disease steps (PDDS) 3.0) or waitlist control group (n=136, 79% female, median PDDS 3.0). Outcomes were measured at baseline, post-intervention (week 12), and follow-up (week 24).

Read more here.