Just read this fascinating article in The Specialty Pharma Times.
“Scientists employed a novel gene therapy technique to reverse and prevent the development of multiple sclerosis (MS) in mice.
For the study, published in Molecular Therapy, investigators used the adeno-associated virus to deliver a gene responsible for a brain protein to the livers of the mouse models. The gene was targeted to the liver because it can induce immune tolerance, and the adeno-associated virus jumpstarted the production of regulatory T cells.
“Using a clinically tested gene therapy platform, we are able to induce very specific regulatory cells that target the self-reactive cells that are responsible for causing multiple sclerosis,” said investigator Brad E. Hoffman, PhD.
Read the rest here.”