Just came across this fascinating article from the Multiple Sclerosis News Today web site

Active brain inflammation appears to be one of the causes driving anxiety and depression in patients with relapsing-remitting multiple sclerosis (RRMS), finds an Italian study published in the journal Neurology. RRMS is the most common form of the disease when patients are initially diagnosed.

Multiple sclerosis patients are often diagnosed with mood disorders. This is not only because of the burden of the disease itself, some studies have suggested, but also due to neuroinflammation. Indeed, inflammation likely contributes to psychiatric disorders, including depression.

Read the full article here.