A daily step count of 9,000 to 10,000 may counteract the risk of death and cardiovascular disease in highly sedentary people.

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Increased step count linked to lower risk regardless of time spent sedentary
Increased step count is linked to lower risk regardless of sedentary time.

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In good news for office workers, a new study from the University of Sydney’s Charles Perkins Centre (Australia) has found increasing your step count may counteract the health consequences of too much sedentary time each day.

The study of over 72,000 people, published in the British Journal of Sports Medicine, found every additional step up to around 10,000 steps a day was linked to reduced risk of death (39 per cent) and cardiovascular disease (21 per cent) regardless of how much remaining time was spent sedentary.

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Previous studies have shown an association between greater daily step count and lower levels of death and CVD, and separate studies have linked high levels of sedentary behaviour with increased risks of CVD and death. However, this is the first to measure objectively, via wrist-worn wearables, if daily steps could offset the health risks of high sedentary behaviour.

Lead author and research fellow Dr Matthew Ahmadi said: “This is by no means a get-out-of-jail card for sedentary people for excessive periods. However, it does hold an important public health message that all movement matters and that people can and should try to offset the health consequences of unavoidable sedentary time by upping their daily step count.”

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Senior author Professor Emmanuel Stamatakis, Director of the Mackenzie Wearables Research Hub at the Charles Perkins Centre, said this growing body of physical activity research using device-based measurement provided huge opportunities for public health.

“Step count is a tangible and easily understood measure of physical activity that can help people in the community, and indeed health professionals, accurately monitor physical activity. We hope this evidence will inform the first generation of device-based physical activity and sedentary behaviour guidelines, which should include key recommendations on daily stepping,” said Professor Stamatakis.

How was the study conducted?

Researchers used data on 72,174 individuals (average age 61; 58% female) from the UK Biobank study – a major biomedical database – who had worn an accelerometer device on their wrist for seven days to measure their physical activity. The accelerometer data were used to estimate daily step count and time spent sedentary: sitting or lying down while awake.

The research team then followed the health trajectory of the participants by linking hospitalisation data and death records.

The median daily step count for participants was 6222 steps/day, and 2200 steps/day (the lowest 5 percent of daily steps among all participants) was taken as the comparator for assessing the impact of increasing step count on death and CVD events.

The median time spent sedentary was 10.6 hours/day, so study participants who spent 10.5 hours/day or more sedentary were considered to have high sedentary time, while those who spent less than 10.5 hours/day sedentary were classified as having low sedentary time.

Adjustments were made to eliminate biases, such as excluding participants with poor health who were underweight or had a health event within two years of follow-up. Researchers also took into account factors such as age, sex, ethnicity, education, smoking status, alcohol consumption, diet and parental history of CVD and cancer.

What did they find?

Over an average 6.9 years follow up, 1633 deaths and 6190 CVD events occurred.

After taking into account other potential influences, the authors calculated that the optimal number of steps per day to counteract high sedentary time was between 9000 and 10000 steps/day, which lowered mortality risk by 39 per cent and incident CVD risk by 21 per cent.

In both cases, 50 per cent of the benefit was achieved between 4000 and 4500 steps daily.

Study limitations

This is an observational study, so it can’t establish direct cause and effect. Although the large sample size and long follow-up allowed the risk of bias to be reduced, the authors acknowledge the possibility that other unmeasured factors could affect results. They add that steps and sedentary time were obtained in a single time point, which could also lead to bias.

Nevertheless, they conclude, “Any amount of daily steps above the referent 2200 steps/day was associated with lower mortality and incident CVD risk, for low and high sedentary time. Accruing between 9000 and 10,000 steps a day optimally lowered the risk of mortality and incident CVD among highly sedentary participants.”

Swapping meat for Quorn lowers bad cholesterol by 10 per cent

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Regularly substituting meat for mycoprotein such as Quorn could help to lower bad cholesterol by 10-percent, which is comparable to switching to a Mediterranean or vegan diet.
Regularly substituting meat for mycoprotein such as Quorn could help to lower bad cholesterol by 10-percent, which is comparable to switching to a Mediterranean or vegan diet.

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Regularly substituting meat for mycoprotein such as Quorn could help to lower bad cholesterol by 10-percent, which is comparable to switching to a Mediterranean or vegan diet.

New research by the University of Exeter, published in Clinical Nutrition, also found substituting meat for Quorn reduces blood glucose and c-peptide concentrations associated with diabetes, cardiovascular disease and all-cause mortality.

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With one in six UK adults suffering from raised cholesterol, the findings indicate that mycoprotein – the high protein, high-fibre food source that’s the main ingredient in Quorn – could play a key role in cholesterol management and improving heart health.

Dr George Pavis, of University of Exeter, led the study and said: “We’re really excited about these results and what they mean for public health. Previous laboratory studies, where all food eaten is controlled and alcohol and caffeine consumption regulated, have clearly shown that daily consumption of mycoprotein reduces bad cholesterol. But this is the first study of its kind to explore the impact of such a dietary intervention in a real-world, home-based setting where participants were not restricted in terms of what else they consumed or did.

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“The findings demonstrate that introducing Quorn foods into a diet on a regular basis helps to significantly lower bad cholesterol, blood glucose and c-peptide concentrations, which is important for boosting heart health and reducing the risk of cardiovascular disease.

“It was particularly interesting to see the scale of the impact that Quorn consumption had in terms of reducing harmful cholesterol, with its performance over four weeks comparable to what we might expect to see from well-established approaches, such as following a Mediterranean diet.”

The remotely delivered study involved 72 overweight adults with high cholesterol levels. Researchers found that participants who ate 180g of Quorn products on a daily basis – equivalent to two servings of Quorn mince – saw a 10-percent reduction in ‘bad’ LDL cholesterol over the four-week study period. This equates to a 0.3 millimole per litre (mmol/l) decrease in bad cholesterol levels in less than one month.

Research has shown how more wholesale healthy dietary changes, such as switching to a Mediterranean or vegan diet, will typically deliver a 0.2 – O.3 mmol/l reduction in bad cholesterol levels after 12 weeks. Researchers at the University of Exeter also noted that typical doses of atorvastatin, the most popular statin prescribed by the NHS to treat high cholesterol, commonly yield a 0.3 – 1.3 mmol/l reduction after 12 months.

According to medical research, a decrease of 0.39 mmol/l in bad cholesterol levels is associated with a 25% lower lifetime risk of heart and circulatory disease. With pharmaceutical trials suggesting that reductions increase in a linear way over time, the researchers suggested further studies should be undertaken to see if the results improve even further when Quorn is eaten over a longer period.

The study – which saw half of the participants (39) given meat and fish products to eat on a daily basis as part of their regular diet, while the other half (33) were provided with Quorn products – also revealed further heart health benefits.

High blood sugar levels and c-peptide concentrations are commonly associated with diabetes and an increased risk of cardiovascular disease and all-cause mortality. The researchers found that study participants who ate Quorn products experienced, on average, a 13-percent drop in blood glucose levels and a 27-percent fall in c-peptide concentrations, compared with the control group. With current data showing that 2.4 million people are at an increased risk of type 2 diabetes in the UK based on high blood sugar levels, these findings demonstrate how mycoprotein could also play a key role in tackling a disease that currently costs an estimated £14 billion a year to treat.

The findings come after the latest annual Health Survey for England estimated that well over half (59-percent) of adults suffer from raised cholesterol and one in ten from diabetes, with both conditions known to cause cardiovascular disease – meaning millions of people could be at risk of a potentially fatal heart attack or stroke.

Sam Blunt, Quorn’s director of sustainability and corporate affairs, said: “The potential cholesterol-lowering effects of Quorn’s mycoprotein were first identified nearly four decades ago and, since then, numerous studies have helped us to understand more about the extent of its cholesterol management capabilities, with its high-fibre content thought to play a key role in this.

“While the benefits of adopting a Mediterranean diet are clear, it’s not always easy to do and this study highlights how, by simply introducing Quorn products into their diet on a regular basis, people may be able to quickly reduce their cholesterol levels and improve their heart health with minimal effort.”

Strategies for Breaking Bad Habits and Cultivating a Healthier, Happier Lifestyle

In today’s fast-paced world, it’s easy to fall into unhealthy habits that can negatively impact our well-being. However, with a well-crafted health roadmap, you can identify these habits and pave the way to a happier and healthier life. In this article from Patient Talk, we’ll explore key strategies to help you break free from detrimental routines and build a brighter future.

Identifying Unhealthy Habits

The journey towards a healthier lifestyle begins with identifying the habits that hinder your well-being. Take a moment to reflect on your daily routine. Are you reaching for that sugary snack too often, staying up late, or skipping your exercise sessions? Recognizing these patterns is the first step toward positive change.

Walking More Often

One of the simplest yet most effective strategies for cultivating healthier habits is to incorporate more walking into your daily life. If you find yourself in a sedentary job, consider taking breaks to stretch your legs. Opt for stairs over elevators, and park farther from entrances to increase your daily step count. Also, look for pedestrian-friendly areas with a high Walk Score to get your steps in.

Saving and Reducing Money Stress

Financial stress can have a major effect on your health. It can lead to sleepless nights, anxiety, and even physical health issues. To foster a healthier lifestyle, look for opportunities to save and reduce money-related stress. Consider budgeting, eliminating unnecessary expenses, and finding ways to boost your income. A solid financial plan is a significant step toward a happier and healthier life.

Setting Goals and Crafting a Plan

To achieve lasting change in your life, setting clear goals and crafting a well-structured plan is essential. Take the time to define what you want to accomplish in your pursuit of a healthier lifestyle. Whether it’s losing weight, improving your fitness, or reducing stress, a roadmap with actionable steps will keep you on track and motivated.

Tracking Your Progress

As you embark on your journey towards better health, tracking your progress becomes a valuable tool. Use journals, mobile apps, or other tracking tools to record your achievements and setbacks. Regularly reviewing your progress provides insights into what’s working and what needs adjustment, helping you stay accountable and motivated.

Establishing a Daily Exercise Regimen

Physical activity is a cornerstone of good health. Incorporating a daily exercise regimen into your routine is crucial. Find an activity you genuinely enjoy, whether it’s a brisk walk in the park, a calming yoga session, or muscle-strengthening workouts at the gym. Consistency is key, and by making exercise a daily habit, you’ll reap the physical and mental benefits that come with it.

Focusing on Nutrition and Hydration

Your diet plays a pivotal role in your overall well-being. Pay close attention to your nutrition by including a variety of fruits, vegetables, and whole grains in your meals. Avoid excessive consumption of processed and sugary foods. Equally important is staying adequately hydrated by drinking plenty of water throughout the day. Proper nutrition and hydration are essential components of a healthier, happier lifestyle.

Breaking free from unhealthy habits and embarking on a journey toward a healthier, happier lifestyle requires dedication and commitment. From identifying the habits that hold you back to walking more often and staying hydrated, with these strategies in your arsenal, you can create a robust health roadmap that leads to a brighter future. Your path to wellness is a journey worth taking, and these steps will empower you to succeed in cultivating a healthier, happier life.

“Jolie’s Corners” – what are they?

In the realm of aesthetic enhancements, the pursuit of natural beauty often leads us to nuanced enhancements that speak volumes through subtlety. Among these, “Jolie’s Corners” emerges as a focal point of interest, capturing the essence of understated elegance in lip aesthetics.

Named after the iconic Angelina Jolie, known for her distinctive lip shape, Jolie’s Corners refer to the slightly upturned corners of the mouth, creating an inviting, subtle smile even in a neutral expression. This feature enhances the lips’ allure without the overt plumpness often sought in cosmetic procedures. It’s a delicate balance between volume and contour, offering a hint of sophistication and confidence.

Achieving Jolie’s Corners typically involves meticulous application of dermal fillers, a domain where hyaluronic acid-based products excel. Hyaluronic acid, a naturally occurring substance in the body, offers a safe and reversible option for those seeking to refine their lip aesthetics. Its ability to attract and retain moisture not only adds volume but also ensures a natural feel and appearance.

The process, performed by skilled practitioners, focuses on enhancing the lip border and strategically augmenting the corners to uplift them slightly. This method respects the natural anatomy of the lips, avoiding overcorrection, and ensuring harmonious results that complement the individual’s facial features.

Jolie’s Corners signify a shift towards personalized beauty enhancements that celebrate individuality. It’s a testament to the evolving understanding of aesthetics, where the goal is not just enhancement but the embodiment of personal style and elegance.

In an era where beauty standards continue to evolve, the preference for subtle and natural enhancements underscores a broader trend toward self-expression and authenticity. Jolie’s Corners, in this context, is not just a cosmetic preference but a reflection of a deeper appreciation for nuanced beauty.

For those considering this elegant lip enhancement, it’s crucial to consult with experienced professionals who understand the art of subtlety in cosmetic procedures. With advancements in dermal filler technology and techniques, achieving the coveted Jolie’s Corners is within reach for those seeking to add a touch of understated charm to their smile.

Conclusion

The website “My Lip Filler” specializes in providing a wide range of dermal fillers and lip enhancers, focusing on hyaluronic acid-based products for cosmetic enhancements such as lip augmentation, wrinkle reduction, and skin rejuvenation. Their offerings include top brands and products designed for various cosmetic needs, including superficial wrinkles, deep wrinkle treatments, and lip fillers. The site emphasizes the benefits of non-surgical cosmetic procedures using hyaluronic acid fillers for their hydrating, rejuvenating, and volume-enhancing properties.

Autism prevalence nearly doubles in Israel between 2017 and 2021. Why do you think this is?

Autism prevalence nearly doubles in Israel between 2017 and 2021.  Why do you think this is?
Autism prevalence nearly doubles in Israel between 2017 and 2021.

Autism diagnoses have increased worldwide over the last decade. Initially, autism rates in Israel were lower than those reported in the USA and Western Europe. However, a new collaborative study by Ben-Gurion University of the Negev, Clalit Healthcare, and the Israeli Ministry of Health has found a dramatic increase in the prevalence of autism in Israel between 2017 and 2021 with a 4-fold increase in young 2–3-year-old children and a 2-fold increase in older ages.

The team, led by BGU’s Prof. Ilan Dinstein, analyzed data from the National Insurance Institute (NII), which manages social security for the entire population of Israel, and from Clalit Healthcare, an HMO that treats 52.8% of the Israeli population. According to NII data, the number of individuals with a formal diagnosis of ASD, 1–17 years old, increased from 14,914 in 2017 to 32,222 in 2021.

“Autism prevalence in children 1–17 years old has almost doubled, autism prevalence in children 2–3 years old has increased by a factor of 4.4. This demonstrates a shift towards early autism diagnosis such that in 2021, the autism prevalence was 1% among 2–3-year-old children and almost 2% among 4–5-year-old children,” the researchers wrote.

From 2017 to 2021, autism prevalence rates of 2–3-year-old (day-care) children increased from 0.27% to 1.19% (>4-fold change), 4–6-year-old (pre-school) children increased from 0.8% to 1.83%, and 8-year-old children increased from 0.82% to 1.56% in NII data. Children 10 years old and older exhibited slightly smaller changes in prevalence rates.

“Our analysis shows that the autism population is growing rapidly, particularly at young ages, which means that education and healthcare services are confronted with a huge challenge to keep up with providing the necessary services,” says Prof. Dinstein of the Departments of Psychology and Cognitive and Brain Sciences and Deputy Director of the Azrieli National Centre for Autism and Neurodevelopment Research at BGU.

Research studies such as these are important benchmarks that government ministries can rely on in their preparations for assisting those with autism. Previous research conducted by Prof. Dinstein and colleagues has demonstrated that autistic children who are diagnosed earlier (as early as two years old), are three times more likely to improve in their communication and social skills in contrast to children who are diagnosed at older ages, but this requires intervention and the availability of services and support.

Dr. Dorit Shmueli, Pediatric Neurologist and head of Child Development in the Community Division at Clalit, “The increase in autism diagnosis is global, for many reasons, the main ones being the expansion of the definition, so that today it includes children with normal cognitive functioning, and an increase in awareness, both by parents and by educational frameworks. In Israel, the increase in requests for autism diagnosis and the dramatic increase in the number of children receiving a diagnosis is clearly felt in child development services, and a comprehensive national plan and allocation of resources are required to respond to the growing needs.”

Prof. Gal Meiri, Director of the Child and Adolescent Psychiatry Unit at Soroka Medical Center and Medical Director of the Azrieli National Research Centre for Autism and Neurodevelopment at Ben-Gurion University of the Negev: “The large increase in the prevalence of autism in Israel corresponds with global data in this field. This increase challenges clinicians and the various systems that provide services to children and people with autism and intrigues researchers in Israel and around the world. Autism is a disorder that accompanies people with autism and their families throughout their lives. The early and intensive intervention has been proven to be effective and advances children with autism, and the new data require attention and preparation by policymakers in this area so that proven interventions can reach every child and every person who needs them.”

According to Ronit Shussel, Director of the Knowledge, Research and Training Division at ALUT: “ALUT, the association that leads the treatment of autism in Israel, sees great importance in concentrating data about the autistic population in Israel and the various services they receive. Without the inclusion of data at the national level, the State of Israel will not be able to provide the population with available and high-quality services required to promote their optimal integration into society and the community. As published in ALUT’s Autism State Report for 2021-2022, there is already a significant shortage of educational, welfare and medical services, and without intervention and service planning, this gap will deepen in the coming years.”

“While it is important that the health system in Israel is diagnosing autism at very young ages, it is equally important that intervention services be available to those who are diagnosed – with such fast growth, this is clearly a challenge. Moreover, these children will likely require support at various levels during adulthood. This study is, therefore, a wake-up call for the government to start planning ahead,” says Prof. Dinstein.

The study was unique in using two separate datasets – one from the NII and one from Clalit – and cross-referencing them. The researchers could, therefore, estimate prevalence rates in the entire population of children in Israel with more confidence. The datasets are considered particularly dependable because the vast majority of parents of children with autism apply to one or the other institution for benefits and services. Revealing equivalent prevalence increases in both data sets demonstrates the reliability and generalizability of the findings and conclusions. Previous prevalence studies in Israel and worldwide have not compared findings across multiple sources in this way.

The study was also unique in breaking down the assessment by age groups corresponding to educational settings – an especially useful feature for government ministries and local municipalities to know where to apply their resources.