Exercise and Pain

Dr. Anthony Machi presented his lecture titled “Exercise and Pain”, which focused on the benefits of physical exercise for the treatment of chronic pain, how exercise works as a treatment, examples of different types of exercise, and recommendations on how to integrate exercise into a treatment plan will be covered.

Should your exercise goals be in minutes or steps? A study suggests they are equally beneficial.

Infographic: Should Your Exercise Goals be in Minutes or Steps?

New research from Brigham and Women’s Hospital researchers reveals that both step and time-based exercise targets are equivalently associated with improved health outcomes, extended lifespan, and reduced risk of cardiovascular disease CREDIT Brigham and Women’s Hospital.

In the age of smartwatches, monitoring step counts has never been easier, but current physical activity guidelines do not explicitly recommend specific step counts for health. A new study by researchers at Brigham and Women’s Hospital, a founding member of Mass General Brigham, suggests that both step- and time-based exercise targets are equivalently associated with lower risks of early death and cardiovascular disease. Thus, whether one chooses a time or step goal may not be as important as choosing a goal aligned with personal preferences.

Physical activity reduces the risk of acquiring chronic illness and infection and promotes longevity. The current U.S. guidelines, last updated in 2018, recommend that adults engage in at least 150 minutes of moderate to vigorous physical activity (e.g., brisk walking) or 75 minutes of vigorous activity (e.g., jogging) per week. At that time, most of the existing evidence on health benefits came from studies where participants self-reported their physical activity. Few data points existed on the relationship between steps and health. Fast forward to the present – with wearables being ubiquitous, step counts are now a popular metric among many fitness tracking platforms. How do time-based goals stack up against step-based ones? Investigators sought to answer this question.

“We recognized that existing physical activity guidelines focus primarily on activity duration and intensity but lack step-based recommendations. With more people using smartwatches to measure their steps and overall health, we saw the importance of ascertaining how step-based measurements compare to time-based targets in their association with health outcomes – is one better than the other?”

For this study, investigators collected data from 14,399 women who participated in the Women’s Health Study, and who were healthy (free from cardiovascular disease and cancer). Between 2011 and 2015, participants aged 62 years and older were asked to wear research-grade wearables for seven consecutive days to record their physical activity levels, only removing the devices for sleep or water-related activities. Throughout the study period, annual questionnaires were administered to ascertain health outcomes of interest, particularly death from any cause and cardiovascular disease. Investigators followed up with participants through the end of 2022.

At the time of device wear, researchers found that participants engaged in a median of 62 minutes of moderate-to-vigorous intensity physical activity per week and accumulated a median of 5,183 steps per day. During a median follow-up of 9 years, approximately 9% of participants had passed, and roughly 4% developed cardiovascular disease. Higher levels of physical activity (whether assessed as step counts or time in moderate-to-vigorous activity) were associated with large risk reductions in death or cardiovascular disease – the most active quarter of women had 30-40% risk reductions compared with the least active quarter. Individuals in the top three quartiles of physical activity outlived those in the bottom quartile by an average of 2.22 and 2.36 months respectively, based on time and step-based measurements, at nine years of follow-up. This survival advantage persisted regardless of body mass index (BMI) differences.

While both metrics are useful in portraying health status, Hamaya explained that each has its advantages and downsides. For one, step counts may not account for differences in fitness levels. For example, if a 20-year-old and 80-year-old both walk for 30 minutes at moderate intensity, their step counts may differ significantly. Conversely, steps are straightforward to measure and less subject to interpretation than exercise intensity. Additionally, steps capture even sporadic movements of every day life, not just exercise, and these kinds of daily life activities are likely carried out by older individuals.

“For some, especially for younger individuals, exercise may involve activities like tennis, soccer, walking, or jogging, all of which can be easily tracked with steps. However, for others, it may consist of bike rides or swimming, where monitoring the duration of exercise is simpler. That’s why it’s important for physical activity guidelines to offer multiple ways to reach goals. Movement looks different for everyone, and nearly all forms of movement are beneficial to our health,” said Hamaya.

The authors note that this study incorporates only a single assessment of time and step-based physical activity metrics. Further, most women included in the study were white and of higher socioeconomic status. Finally, this study was observational, and thus, causal relations cannot be proven. In the future, Hamaya aims to collect more data via a randomized controlled trial to better understand the relationship between time and step-based exercise metrics and health.

Longer sprint intervals can improve muscle oxygen utilization compared to shorter intervals.

Using a multifaceted approach, scientists reveal the ideal duration and repetition of sprint interval training
Using a multifaceted approach, scientists reveal the ideal duration and repetition of sprint interval training.


Physical activities like jogging, walking, cycling, and sprinting are known to engage the musculoskeletal system and result in energy utilisation. Sprint interval training (SIT) is a type of sprinting exercise that involves cycles of intense exercise followed by a short duration of rest. How the durations of exercise and rest are structured can affect the impact of SIT on physiological responses. In recent years, the field of sports physiology has witnessed increased interest in optimizing SIT protocols. This surge can enhance the recognition of SIT’s efficacy in improving athletic performance and overall well-being, highlighting its versatility to promote health and fitness.


Explaining the motivation behind their research work, Yamagishi says, “Establishing a minimum dose of exercise training to bring about training benefits, such as aerobic fitness, has been one of my main research interests.  Due to the support from Prof. Kawakami and other co-authors, along with the collaboration with Waseda University, this unique research work using a multifaceted approach was possible.”
The team of researchers matched two different sprint interval exercises (SIE) for the total duration of sprint and sprint-to-rest ratio. They analyzed the influence of SIE on physiological and metabolic responses by examining pulmonary oxygen uptake (V̇O2) levels and changes in tissue oxygenation index (∆TOI) in thigh muscles. Additionally, they utilized the T2-weighted magnetic resonance imaging (MRI) technique to assess the activation of thigh muscles. researchers’ team matched two sprint interval exercises (SIE) for the sprint and sprint-to-rest ratio duration

The researchers highlight that SIE20, comprising two 20-second sprints with 160-second recovery, outperformed SIE10, which involved four 10-second sprints with 80-second recovery. While both the SIE protocols significantly increased whole-body and peripheral oxidative metabolism and the activation of the major thigh muscles, as indicated by the increases in V̇O2 levels, ∆TOI and MRI T2 values, respectively, greater peripheral oxidative metabolism was achieved with SIE20. They also observed that successive sprint repetitions in SIE10 did not correlate with greater oxidative metabolism.

Elaborating on the real-life applications and impact of the present research, Yamagishi says, “In today’s fast-moving world, lack of time is a major hindrance to regular physical activity. However, the exercise modalities employed in our study require less than 15 minutes to complete and provide considerable health benefits.” 

Running under a four-minute mile could be the key to a long and healthy life

A new study released to mark the 70th anniversary of Sir Roger Bannister’s sub-four-minute mile record has revealed the first 200 runners to follow in his footsteps also share another remarkable trait

A new study released to mark the 70th anniversary of Sir Roger Bannister’s sub-four-minute mile record has revealed the first 200 runners to follow in his footsteps also share another remarkable trait.

Investigators in Australia and Canada conducted the study, which found that the 200 elite runners live, on average, almost five years longer than the general population.

Professor Mark Haykowsky, the Research Chair in Aging and Quality of Life in the Faculty of Nursing at the University of Alberta, says the findings published in the British Journal of Sports Medicine demonstrate the vital importance of aerobic fitness.

Professor Haykowsky says: “Breaking the four-minute mile was an extraordinary achievement 70 years ago and revealed just what the human body can achieve. It set off a wave of runners following in Sir Roger’s mighty footsteps.

“Remarkably we found that like Sir Roger, who lived to the ripe old age of 88, most of the first runners also lived well into their 70s, 80s and a majority are alive and healthy today.”

The multi-national team tracked down the health records of the first 200 people to complete the sub-four-minute mile. This included runners from the UK, Australia, France, New Zealand, and the United States who were born between 1928 to 1955. All 200 runners are men, and a majority were still alive.

Professor Andre La Gerche, a world-renowned sports cardiologist who heads the HEART Laboratory supported by St Vincent’s Institute of Medical Research and the Victor Chang Cardiac Research Institute in Australia, says: “Our study set out to see how exercise affected elite athletes over the long term. We know that elite athletes have bigger hearts due to their sustained aerobic output and there was some belief that this could affect their health and longevity, but we found the opposite.

“Five years of extra life compared to average is very significant, especially when we found that many of these runners not only enjoyed long lives but were also healthy too.

“Not everyone needs to be able to run a sub-four-minute mile to enjoy good health long into old age, but they need to exercise regularly and push themselves aerobically.”

The world record for the mile now stands at 3.43 and is held by Hicham El Guerrouj of Morocco. Ollie Hoare is the fastest Australian (3.47.48) and Kevin Sullivan holds the Canadian record (3.50.26) both of which were set at the Bislett Games in Oslo, Norway. No female runner has yet broken the four-minute barrier. The women’s world record is currently at 4:07.64, set by Faith Kipyegon of Kenya in 2023.

Fibromyalgia & Chronic Pain Relief With Gentle Stretches – Lying Down

Finding the right intensity of movement to help relieve fibromyalgia and other chronic pain is different from person to person. While movement is important to feeling better, too much can cause a flare-up. The gentle stretches and exercises in this video, when done at one’s own pace, may help relieve the pain. Fibromyalgia and other chronic pain conditions can cause pain, fatigue, sleep disturbances, and even emotional/mental health issues.