Cognitive dysfunction

Posted on Cognitive dysfunction, Multiple Sclerosis

Research shows promise for cognitive rehabilitation for multiple sclerosis

Improvements in memory performance, perceived memory ability in daily life, and functional performance, warrant more extensive clinical trials using TELE-self-GEN in MS therapy
Improvements in memory performance, perceived memory ability, and functional performance warrant more extensive clinical trials using TELE-self-GEN in MS therapy.

A preliminary study demonstrates the potential for a new treatment for memory problems in people with multiple sclerosis.

The pilot study involved ten participants with memory impairments related to multiple sclerosis (MS). It aimed to determine the feasibility and impact of six online sessions of TELE-Self-GEN, delivered via Zoom. Lead author Yael Goverover, PhD, OTR/L, a professor in New York University’s Department of Occupational Therapy and a visiting scientist at Kessler Foundation, explained that TELE-Self-GEN integrates memory strategies within a metacognitive framework to help individuals manage their cognitive challenges.

Participants reported high satisfaction levels, citing the convenience and accessibility of the virtual format. Most notably, they experienced improvements in memory tasks and their ability to perform daily activities.

“Our findings are promising, demonstrating that remote interventions can be both effective and satisfying for participants. Delivering therapy to individuals at home is not only convenient,” Dr. Goverover noted, “it expands access to cognitive rehabilitation designed to improve how individuals function in their daily lives.”

The intervention focuses on ‘self-generated learning,‘ a technique that encourages patients to create personal connections with everyday tasks, enhancing memory retention and recall. This method of association has proven effective in fostering greater independence and confidence among users, ultimately contributing to improved quality of life.

Posted on Cognitive dysfunction, Eye health, Multiple Sclerosis

A new study reveals a breakthrough in the treatment of visual and cognitive impairments in multiple sclerosis.

A pilot study conducted by researchers at the Kessler Foundation showed promising results in using methylphenidate to improve oculomotor function in individuals with multiple sclerosis (MS). The findings could have significant implications for the treatment of visual and cognitive impairments associated with multiple sclerosis (MS).

Silvana Costa, PhD

Dr. Costa is a research scientist at the Centers for Neuropsychology, Neuroscience, and Multiple Sclerosis Research at the Kessler Foundation. CREDIT Kessler Foundation

In a pilot randomized placebo-controlled trial, 11 participants with MS were randomly assigned to receive either methylphenidate or a placebo for four weeks. After a seven-day washout period, they underwent a crossover treatment for four more weeks. Assessments of oculomotor speed using the King-Devick test and information processing speed were conducted before and after each treatment phase.

“We noticed a significant increase in the participants’ eye movement speed when they were given methylphenidate compared to when they were given the placebo,” said Timothy J. Rich, PhD, OTR/L, research scientist at the Center for Stroke Rehabilitation Research at Kessler Foundation. “This improvement in eye movement speed was directly linked to better performance on tasks that involve hand-eye coordination, which is important for everyday activities.”

Dr. Silvana L Costa, who works as a research scientist at the Centers for Neuropsychology, Neuroscience, and Multiple Sclerosis Research at Kessler Foundation, and is also a co-author of the study, stated, “Our results indicate that methylphenidate might offer valuable benefits as a treatment for individuals with MS, particularly for those who are dealing with oculomotor deficits impacting their visual processing speed and, consequently, their overall quality of life.”

“These results are promising,” noted Dr. Costa, “offering a potential pathway to mitigate some of the cognitive and visual symptoms that are prevalent in MS.”

Posted on Alzheimer's, Cognitive dysfunction

Protecting Your Brain Health – How Science Is Revolutionizing Cognitive Health

We’re living in a neuroscience revolution, with more ways to detect and treat brain disorders than was imaginable just a few decades ago. Hear from Dr Longo, a leading expert in the research and treatment of neurological conditions, about the work being done at Stanford to transform the field and offer hope to the millions of people suffering from cognitive impairment due to Alzheimer’s and other neurodegenerative conditions. From novel blood tests and brain imaging approaches to emerging treatments, Dr Longo will explain how he and his fellow scientists work to detect problems earlier, create strategies to delay the onset of cognitive loss, reverse impairment once it begins, and increase brain resiliency for all people. He’ll also offer information you can use, starting now, to help protect your own brain health far into the future.

Posted on Cognitive dysfunction

Brain Fog: Causes and Cures

In this episode of I CARE FOR YOUR BRAIN with Dr. Sullivan, board-certified neuropsychologist Dr. Karen D. Sullivan discusses brain fog. Watch and learn about six causes of this mental over- or under-stimulation and decreased working memory, as well as evidence-based treatments for improving the symptoms starting today.

Posted on Cognitive dysfunction

How to Treat Mild Cognitive Impairment


This video provides a step-by-step guide on addressing Mild Cognitive Impairment (MCI), offering essential treatment strategies and insights. From understanding the fundamentals of MCI to exploring advanced therapeutic options, Dr. Kernisan demystifies the process of managing this prevalent condition.