In this clip (6 of 10): Imaging studies have shown changes in brain anatomy in people who are longtime chronic pain patients, such as accelerated loss of gray matter. “Psychologically based” approaches such as meditation and yoga may be protective, although more study is needed. This clip is part of the lecture “The Neural Basis of Mind-Body Pain Therapies” by M. Catherine Bushnell, Ph.D., scientific director of the Division of Intramural Research, NCCAM, NIH. This lecture, given at NIH in 2013, is part of the NCCAM Online Continuing Education Series.