A drug called clemastine was found to have remyelinating effects in animals many years ago. Recently, a new drug called PIPE-307 has emerged, which may be an improvement over clemastine. It is more targeted towards the M1 receptor, believed to mediate remyelinating effects. PIPE-307 also has excellent penetration into the central nervous system and is highly potent. This video provides an overview of the research conducted on PIPE-307 so far and the ongoing trials.