What is the cause of MS? For decades, the cause has eluded scientists. Here, I discuss attempts to look for a singular cause such as Nitrates, Saturated fat and dairy, Vertebral artery abnormalities, Thymus overactivity, Amalgam toxicity, Chronic yeast infection (candida overgrowth), and CCSVI. I then discuss risk factors for MS such as EBV, Diet, Vitamin D levels, Sunlight, genetics, sunlight exposure I then give my opinion on whether we will find a cause of multiple sclerosis.