News flash – New analysis method of metabolites accurately predicts whether a child has autism

Products of metabolic processes altered in children with autism could enable earlier diagnosis
Products of metabolic processes altered in children with autism could enable earlier diagnosis

“Scientists have developed a new, highly accurate method that analyzes metabolic biomarkers to assess whether a child is on the autism spectrum, according to a study published in PLOS Computational Biology.

Autism spectrum disorder affects about 1.5 percent of all children, but its exact cause remains unknown, and diagnosis requires a multidisciplinary team of doctors. Previous research has revealed certain differences in metabolic processes between children on the autism spectrum and neurotypical children. However, researchers have struggled to translate these differences into new diagnostic tools.”

Read the rest of the article here.

What Autism Feels Like – from an autism mom! This is very important for you to watch! Please do!

What Autism Feels Like
What Autism Feels Like

What Autism Feels Like – from an autism mom!

NB There could be triggers for people on the autism spectrum!

Reye’s Syndrome – what everyone needs to know!

Reye's syndrome
Reye’s syndrome

Reye’s syndrome is a very rare disorder that can cause serious liver and brain damage. If it’s not treated promptly, it may lead to permanent brain injury or death.

Reye’s syndrome mainly affects children and young adults under 20 years of age.


Symptoms of Reye’s

The symptoms of Reye’s syndrome usually begin a few days after a viral infection, such as a coldflu or chickenpox.

Initial symptoms can include:

vomiting repeatedly

tiredness and lack of interest or enthusiasm

rapid breathing

fits (seizures)

As the condition progresses, the symptoms may get more severe and more wide-ranging, and can include:

irritability, or irrational or aggressive behaviour

severe anxiety and confusion that’s sometimes associated with hallucinations

coma (loss of consciousness)

When to get medical advice

As Reye’s syndrome can be fatal, it’s vital that you get medical advice if you think your child may have it.


loses consciousness

has a fit or convulsions (violent, irregular limb movements)

You should contact your GP if, after having a cold, flu or chickenpox, your child is:

vomiting repeatedly

unusually tired

displaying personality or behavioural changes (see above)

Although it’s unlikely these symptoms will be caused by Reye’s syndrome, they still need to be checked by a doctor.

Tell your GP if your child has taken aspirin, because the use of aspirin in children has been linked to Reye’s syndrome (see below).

But even if your child hasn’t taken aspirin, Reye’s syndrome shouldn’t be ruled out.

What causes Reye’s syndrome?

The exact cause of Reye’s syndrome is unknown, but it most commonly affects children and young adults recovering from a viral infection – typically, but not exclusively, a cold, flu or chickenpox.

In most cases, aspirin has been used to treat their symptoms, so aspirin may trigger Reye’s syndrome.

In Reye’s syndrome, it’s thought that tiny structures within the cells called mitochondria become damaged.

Mitochondria provide cells with energy and they’re particularly important for the healthy functioning of the liver.

If the liver loses its energy supply, it begins to fail. This can cause a dangerous build-up of toxic chemicals in the blood, which can damage the entire body and can cause the brain to swell.

Diagnosing Reye’s syndrome

As Reye’s syndrome is so rare, other conditions that can cause similar symptoms need to be ruled out. These include:

meningitis – inflammation of the protective membranes surrounding the brain and spinal cord

encephalitis – inflammation of the brain

inherited metabolic disorders – conditions, such as medium-chain acyl-CoA dehydrogenase deficiency (MCADD), that affect the chemical reactions that occur in your body

Blood tests and urine tests can help detect if there’s a build-up of toxins or bacteria in the blood, and they can also be used to check if the liver is functioning normally.

Tests may also be carried out to check for the presence or absence of certain chemicals that could indicate an inherited metabolic disorder.

Other tests that may be recommended include a:

CT scan to check for brain swelling

lumbar puncture – where a sample of fluid is removed from the spine using a needle to check for bacteria or viruses

liver biopsy – where a small sample of liver tissue is removed and examined to look for distinctive cell changes associated with Reye’s syndrome

Treating Reye’s syndrome

If Reye’s syndrome is diagnosed, your child will need to be immediately admitted to an intensive care unit.

Treatment aims to minimise the symptoms and support the body’s vital functions, such as breathing and blood circulation.

It’s also essential to protect the brain against permanent damage that can be caused by the brain swelling.

Medicines may be given directly into a vein (intravenously), such as:

electrolytes and fluids – to correct the level of salts, minerals and nutrients, such as glucose (sugar), in the blood

diuretics – medications to help rid the body of excess fluid and reduce swelling in the brain

ammonia detoxicants – medications to reduce the level of ammonia

anticonvulsants – medications to control seizures

A ventilator (breathing machine) may be used if your child needs help with breathing.

Vital body functions will also be monitored, including the heart rate and pulse, the air flow to their lungs, blood pressure and body temperature.

Once the swelling in the brain has reduced, the other functions of the body should return to normal within a few days, although it may be several weeks before your child is well enough to leave hospital.

Possible complications

As a result of advances in diagnosing and treating Reye’s syndrome, the majority of children and young adults who develop it will survive, and some will make a full recovery.

However, Reye’s syndrome can leave some people with a degree of permanent brain damage caused by the swelling of their brain.

Long-term difficulties sometimes associated with Reye’s syndrome include:

poor attention span and memory

some loss of vision or hearing

speech and language difficulties

problems with movement and posture

difficulty swallowing

problems with everyday tasks, such as dressing or using the toilet

If your child develops any long-term problems, an individual care plan will be drawn up to address their needs. The plan will be reassessed as they get older.

Read more about living with disability and care and support.

Preventing Reye’s syndrome

Because of the possible link between aspirin and Reye’s syndrome, aspirin should only be given to children under 16 on the advice of a doctor when it’s felt the potential benefits outweigh the risks.

Children under 16 should also not take any products containing:

acetylsalicylic acid


salicylic acid


salicylate salts

Some mouth ulcer gels and dental gels contain salicylate salts. These shouldn’t be given to children under 16 years of age. There are alternative products that are suitable for under 16s – ask your pharmacist for advice.

What is a multiple sclerosis relapse? And how can it be treated?

What is a multiple sclerosis relapse?
What is a multiple sclerosis relapse?

What is a multiple sclerosis relapse? And how can it be treated?

Dr. Daniel Ontaneda, Cleveland Clinic Mellen Center for Multiple Sclerosis Treatment and Research tells us more in this fascinating video.

You can read the advice of our readers here.